Through an interactive performance format, Aperio's programming examines the art music of South and North America, focusing particularly on musical contributions drawn from many indigenous and foreign cultures. The ensemble advocates for the creation and promotion of new works by both emerging and established composers, often exploring the relationship between selected repertoire and other art forms.

In the spirit of this mission, the organization is committed to expanding classical music audiences through extensive community and educational outreach programs, with a particular focus on underserved communities in the Houston area.